Reducing Synaptic Plasticity Decreases Resilience to Depression and Anxiety in an ASCL1 Mouse Model

Abstract

Synaptic plasticity, the ability of synapses to strengthen or weaken over time in response to activity, plays a crucial role in the brain’s adaptability and function. This paper examines the impact of synaptic plasticity on resilience to depression and anxiety in an ASCL1 mouse model. By studying the molecular and cellular mechanisms of synaptic changes, how these changes affect behavioral outcomes related to stress and emotional regulation analysis. Through the research and findings of this paper, a deeper understanding of the relationship between the enhancement of synaptic plasticity and mood changes, and provide more treatment ideas for depression and emotion-related diseases.