Whether Carotenoids and Quercetin Affect the Proliferation andExpression of PPARγ Protein in Leukemia K562 Cells

Authors

  • Ziyan Liu Author

DOI:

https://doi.org/10.61173/58mg8711

Keywords:

carotenoids, PPARγ protein, K56 cells

Abstract

Carotenoids are some of the most abundant pigments in nature, ranging from yellow to red. Carotenoids can divide into
two categories: carotenoids composed of hydrocarbon elements and lutein-containing oxygen elements. They are lipidsoluble pigments, and some contain carbonyl or enol groups, which are water-soluble. Carotenoids absorb visible light
from 400 nm to 600 nm, while special ones such as octa-hydro lycopene and hexahydrolycopene only absorb ultraviolet
light. Quercetin is a flavonoid compound widely found in fruits and vegetables. Its chemical structure phenolic hydroxyl
group is the basis of antioxidant action, which can be used for hydrogen to quench oxygen free radicals. It is oxidized
to form a highly stable catechol structure. It has a variety of biological activities and pharmacological effects, such as
expanding coronary blood vessels and inhibiting tumor cell proliferation. This paper shows that the K562 cell growth
rate in carotenoids and quercetin treatment groups was slower than the control group.

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Published

2023-06-01

Issue

Section

Articles