Nanoparticles in breast cancer therapy

Abstract

Nanoparticles have been popular as therapeutic agents for breast cancer due to their distinct properties and wide range of applications. Nanoparticles, which are extremely small and have a high surface area-to-volume ratio, have several benefits, including improved drug solubility, precise delivery to specific targets, and longer circulation in the body. Their targeted drug delivery systems minimize exposure to neighboring healthy cells, reducing potential side effects. Encapsulation of drugs within nanoparticles improves efficacy and stability while protecting them from premature metabolism and degradation. Additionally, nanoparticles facilitate combination therapy by carrying multiple therapeutic agents simultaneously, targeting different aspects of cancer progression. Lipid-based, polymer-based, inorganic, and hybrid nanoparticles are prominent types of nanoparticles utilized in clinical breast cancer treatment. Nanoparticle-based cancer therapy utilizes nanoparticles to deliver therapeutic agents directly to the tumor site, maximizing the therapeutic effect. This article provides a thorough examination of various nanoparticle varieties and their therapeutic applications in the treatment of breast cancer.