Research progress on the genetic factors and treatment methods of gynecological malignant tumors

Abstract

Gynecological malignancies include a variety of types, such as CC, EC, and OC, and the degree of malignancy varies greatly among different types and patients. In addition, studies targeting gynecological malignancies have found that genetic alterations in pathways and gene mutations leading to abnormal cell proliferation can lead to the appearance of cancer. Further research is needed in this area to explore preventive measures to reduce the incidence in high-risk women. This article analyzes the genetic mechanism, environmental factors, symptoms, and treatment of gynecological malignancies. Although optimization of treatment has reduced cancer mortality, the malignancy of tumors remains high, and most patients are at risk of recurrence. Multiple genes related to the development of gynecological malignancies and the limitations of traditional treatment methods such as chemotherapy and radiotherapy were also mentioned, emphasizing the importance of research targeting genetic mechanisms in order to provide more accurate and personalized screening and prevention programs. This article highlights the important role of genetic factors in the occurrence of gynecological malignancies, especially EC and OC. It points out the relationship between some key genetic variants and gynecological cancers, which provides a reference for future research. In addition, the long-term efficacy and safety of emerging therapies such as targeted therapy and immunotherapy, which are not mentioned in this article, also exhibit large prospects and need to be further verified and explored.