From Sun to Clock: Exploring the Interplay Between Circadian Rhythms and Systemic Lupus Erythematosus

Abstract

Systemic lupus erythematosus (SLE) has a complicated interaction with circadian rhythms, which influences immune function and disease activity. This study investigates the role of circadian dysregulation in SLE pathogenesis, specifically analysing changes in immune cell rhythms, sleep patterns, and nocturnal blood pressure in afflicted people. By deciphering this complex dynamic, researchers hope to gain new insights into SLE’s underlying processes and potential treatment approaches. Tailoring therapeutic techniques to address circadian factors may offer promise for improving clinical results and quality of life in SLE patients. Overall, this study emphasises the importance of knowing the circadian component in autoimmune illnesses such as SLE, which opens new possibilities for individualised and targeted therapies to reduce disease burden.