The Application and Research Progress of Hydrogel Loading Stem Cells in Bone Regeneration

Abstract

Nowadays, osteogenesis technology is one of the hot topics in the current orthopedic field. Globally, improving the stability and efficiency of bone regeneration has become a problem that society has been studying. Due to its good tunability, compatibility, and combination ability, hydrogel is gradually applied to bone regeneration technology. Stem cells can differentiate and copy, and have certain clinical potential in the regeneration and treatment of bone tissue. In recent years, many new types of hydrogel materials have been developed, and some are expected to be applied to clinical trials. Likewise, stem cell therapy is also at the forefront of medical research today. Many types and good characteristics make part of them smoothly applied to bone regeneration. In this review, the experimental data and research results of cutting-edge and developmental hydrogel-loading stem cell technology in the field of bone regeneration are collected, and the development and application of this technology will be summarized. The article contains the nature, preparation, and development of hydrogel; discusses the effective role of hydrogel and stem cells in the field of bone regeneration; combined with biological factor therapy and the future development of new technologies. The article also focuses on the development and application of different types of new composite hydrogel. At the same time, these hydrogels make bone regeneration technology more efficient and stable through stem cells with different characteristics. Therefore, this review tells the far-reaching impact of this technology on the future of bone regeneration technology, skeletal development, and even organizational repair.