Carbon neutrality is an unstoppable trend. In the context of increasingly stringent policy constraints, pushing regulatory rigidity to its limits, “chemists” face severe challenges in both survival and transformation. How to respond to these changes and achieve a breakthrough is the mission and responsibility of “chemists.” This article delves into the internal mechanisms of carbon neutrality, exploring the contributions and feasible paths for chemists within this vision. By enhancing management through park circularity and technological innovation through process intensification, chemists can achieve a victorious breakthrough under the carbon neutrality vision.